Recombinant Mouse Zinc transporter 6 (Slc30a6), partial

中文名稱：

小鼠Slc30a6重組蛋白
貨號：

CSB-YP803887MO1
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Slc30a6重組蛋白
貨號：

CSB-EP803887MO1
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Slc30a6重組蛋白
貨號：

CSB-EP803887MO1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Slc30a6重組蛋白
貨號：

CSB-BP803887MO1
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Slc30a6重組蛋白
貨號：

CSB-MP803887MO1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slc30a6
Uniprot No.：

Q8BJM5
別名：

Slc30a6; Znt6; Zinc transporter 6; ZnT-6; Solute carrier family 30 member 6
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment.
基因功能參考文獻：
1. overexpression of ZnT6 causes growth inhibition, znT6 functions in zinc homeostasis and transport PMID: 11997387
2. Expression of zinc transporter ZnT6 in mouse choroid epithelial cells suggests that the choroid plexus plays an important role in regulation of zinc homeostasis in the brain. PMID: 15257151
3. There were no differences between the mRNA expression levels of ZnT family members in undifferentiated Rcho-1 cells and differentiated Rcho-1 cells. PMID: 15475177
4. Increased ZnT-6 immunostaining in neurons containing cytoplasmic inclusions in MCI, AD, and PD suggests a role for ZnT-6 in the pathogenesis of these lesions. PMID: 16772872
5. Our results revealed that ZNT7 immunoreactivity was abundantly expressed in the nerve cells of the mouse DRG.Double immunofluorescence labeling of ZNT7 and TGN38 revealed a colocalization of the two antigens in the Golgi apparatus. PMID: 17720550
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亞細胞定位：

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Found in vesicles.
蛋白家族：

Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
組織特異性：

Expressed in brain and liver, and to a lower extent also in lung. Highly expressed in brain (at protein level).
數據庫鏈接：

KEGG: mmu:210148

STRING: 10090.ENSMUSP00000136503

UniGene: Mm.243943