Recombinant Mouse Sarcolemmal membrane-associated protein (Slmap), partial

中文名稱：

小鼠Slmap重組蛋白
貨號：

CSB-YP666277MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Slmap重組蛋白
貨號：

CSB-EP666277MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Slmap重組蛋白
貨號：

CSB-EP666277MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Slmap重組蛋白
貨號：

CSB-BP666277MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Slmap重組蛋白
貨號：

CSB-MP666277MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slmap
Uniprot No.：

Q3URD3
別名：

Slmap; Kiaa1601; Slap; Sarcolemmal membrane-associated protein; Sarcolemmal-associated protein
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

May play a role during myoblast fusion.
基因功能參考文獻：
1. These data demonstrate that SLMAP is a regulator of E-C coupling at the level of the SR and its perturbation results in progressive deterioration of cardiac electrophysiology and function. PMID: 22180652
2. SLMAP may be an important regulator of glucose uptake or involved in GLUT-4 fusion/translocation into the plasma membrane of mouse abdominal adipose tissue; changes in SLMAP expression are linked to hyperglycemia and diabetes. PMID: 21785580
3. the genomic structure; SLMAP sequences directed a reporter green fluorescent protein (GFP) to the centrosome, and deletions of the newly identified N-terminal sequence from SLMAP prevented the centrosomal targeting PMID: 15126628
4. The cardiac-specific expression of SLMAP isoforms that can be targeted to distinct subcellular membranes, self assemble, and interact with the myofibril suggests a potential role in the structural arrangement of the E-C coupling apparatus. PMID: 15591093
5. Microvasculature in db/db mice undergoes significant changes in vascular function with endothelial component of vascular dysfunction specifically correlating with overexpression of SLMAP. PMID: 15764684
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亞細胞定位：

Cell membrane, sarcolemma; Single-pass type IV membrane protein. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, myofibril, sarcomere, Z line.; [Isoform 1]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centrosomes in a microtubule- dependent manner.; [Isoform 2]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the centrosomes in a microtubule- dependent manner.
蛋白家族：

SLMAP family
組織特異性：

Expressed in proliferating myoblasts and differentiated myotubes (at protein level). Expressed in myoblasts, cardiac and skeletal muscles.
數(shù)據(jù)庫鏈接：

KEGG: mmu:83997

STRING: 10090.ENSMUSP00000046956

UniGene: Mm.36769