Recombinant Mouse Protein Tob2 (Tob2)

中文名稱：

小鼠Tob2重組蛋白
貨號(hào)：

CSB-YP862418MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Tob2重組蛋白
貨號(hào)：

CSB-EP862418MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Tob2重組蛋白
貨號(hào)：

CSB-EP862418MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tob2重組蛋白
貨號(hào)：

CSB-BP862418MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tob2重組蛋白
貨號(hào)：

CSB-MP862418MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tob2
Uniprot No.：

Q9JM55
別名：

Tob2; Protein Tob2; Transducer of erbB-2 2
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-345
氨基酸序列

MQLEIKVALN FIISYLYNKL PRRRADLFGE ELERLLRKKY EGHWYPEKPL KGSGFRCVHI GEVVDPVVEL AAKRSGLAVE DVRANVPEEL SVWIDPFEVS YQIGEKGVVK VLYLGDSEAS GTPELDKEIK SSFNPDAQVF VPIGSQDSSL SSSPSPSFGQ SPSPTFIPRS AQPITFTTAS FAATKFGSTK MKKGGGASGG VSVGGSGAGG QQPPPQQPRM ARSPTKNLLK HKSLSLSMHS LNLIPANPAP QSQLSPNAKE FVYNGGGSPS LFFDGVEGPS TSTTAPFGSG GASTCNSSSF DVSQVFGGGA NSLFLEKSPF VEGLSYNLNT MQYPNQPFQP VVLAN
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.
基因功能參考文獻(xiàn)：
1. These results revealed a new molecular mechanism that fine-tunes osteoblast differentiation through miR-5100/Tob2/osterix networks. PMID: 27873073
2. miR-322 and its target protein Tob2 modulate Osx mRNA stability PMID: 23564456
3. Tob2 protein suppresses PPARgamma2 transcription by inhibiting BMP2-induced Smad1/5 phosphorylation through its interaction with Smad6 and by sequestering C/EBPalpha from the PPARgamma2 promoter. PMID: 23071089
4. Tob2 negatively regulates formation of osteoclasts by suppressing RANKL expression through its interaction with vitamin D receptor PMID: 18358842
蛋白家族：

BTG family
組織特異性：

Ubiquitous.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:57259

STRING: 10090.ENSMUSP00000061390

UniGene: Mm.323595