Recombinant Mouse Protein BTG1 (Btg1)

中文名稱(chēng)：

Recombinant Mouse Protein BTG1(Btg1)
貨號(hào)：

CSB-YP002863MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

Recombinant Mouse Protein BTG1(Btg1)
貨號(hào)：

CSB-EP002863MO
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

Recombinant Mouse Protein BTG1(Btg1)
貨號(hào)：

CSB-EP002863MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

Recombinant Mouse Protein BTG1(Btg1)
貨號(hào)：

CSB-BP002863MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

Recombinant Mouse Protein BTG1(Btg1)
貨號(hào)：

CSB-MP002863MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Btg1
Uniprot No.：

P62325
別名：

Btg1; Protein BTG1; B-cell translocation gene 1 protein
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full length protein
表達(dá)區(qū)域：

1-171
氨基酸序列

MHPFYTRAAT MIGEIAAAVS FISKFLRTKG LTSERQLQTF SQSLQELLAE HYKHHWFPEK PCKGSGYRCI RINHKMDPLI GQAAQRIGLS SQELFRLLPS ELTLWVDPYE VSYRIGEDGS ICVLYEASPA GGSTQNSTNV QMVDSRISCK EELLLGRTSP SKNYNMMTVS G
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Anti-proliferative protein.
基因功能參考文獻(xiàn)：
1. Subventricular zone stem cells are endowed with a hidden supply of self-renewal capacity, coupled to cell cycle acceleration and emerging after ablation of the quiescence-maintaining Btg1 gene and following exercise. PMID: 28247022
2. Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development. PMID: 27036158
3. our results identify BTG1 as a tumor suppressor in leukemia that, when deleted, strongly enhances the risk of relapse in IKZF1-deleted B-cell precursor acute lymphoblastic leukemia, and augments the glucocorticoid resistance phenotype mediated by the loss of IKZF1 function. PMID: 27979924
4. the findings provide evidence for a role of Btg1 regulating the initial differentiation of cartilage and tendons. PMID: 26662056
5. BTG1 overexpression or knockdown improved or impaired insulin signaling respectively. PMID: 26396236
6. Btg1 regulates the proliferation of cerebellar granule precursors selectively through cyclin D1. PMID: 26524254
7. these data show that both Btg1 and Btg2 are required for normal vertebral patterning of the axial skeleton, but each gene contributes differently in specifying the identity along the anterior-posterior axis of the skeleton. PMID: 26218146
8. Btg1 gain- and loss-of-function experiments were consistent with the pattern of expression of this gene in the developing digits. We detected a negative influence of BTG1 in the progress of cartilage maturation and a positive influence in the formation of fibrogenic tissue. PMID: 26662056
9. Antiproliferative BTG1 may participate in the activation-induced cell death of microglia by lowering the threshold for apoptosis. PMID: 14634089
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蛋白家族：

BTG family
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:12226

STRING: 10090.ENSMUSP00000038863

UniGene: Mm.23811