Recombinant Mouse Myogenic factor 6 (Myf6)

中文名稱：

小鼠Myf6重組蛋白
貨號：

CSB-YP015288MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Myf6重組蛋白
貨號：

CSB-EP015288MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Myf6重組蛋白
貨號：

CSB-EP015288MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Myf6重組蛋白
貨號：

CSB-BP015288MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Myf6重組蛋白
貨號：

CSB-MP015288MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Myf6
Uniprot No.：

P15375
別名：

Myf6; Mrf4; Myf-6; Myogenic factor 6; Myf-6; Herculin; Muscle-specific regulatory factor 4
種屬：

Mus musculus (Mouse)
蛋白長度：

Full length protein
表達區域：

1-242
氨基酸序列

MMMDLFETGS YFFYLDGENV TLQPLEVAEG SPLYPGSDGT LSPCQDQMPQ EAGSDSSGEE HVLAPPGLQP PHCPGQCLIW ACKTCKRKSA PTDRRKAATL RERRRLKKIN EAFEALKRRT VANPNQRLPK VEILRSAISY IERLQDLLHR LDQQEKMQEL GVDPYSYKPK QEILEGADFL RTCSPQWPSV SDHSRGLVIT AKEGGANVDA SASSSLQRLS SIVDSISSEE RKLPSVEEVV EK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
基因功能參考文獻：
1. findings identified miR-374b directly targets Myf6 and negatively regulates myogenesis PMID: 26498529
2. Mrf4 has a role in priming embryonic founder cells to become adult muscle stem cells PMID: 23623977
3. Intrinsic muscle factor MRF4 plays an important role in maintenance of neuromuscular junctions. PMID: 21278612
4. Data demonstrated that Myf6 is Tceal7 upstream transactivators using transcriptional assays. PMID: 20307260
5. MRF4 targets the proximal region of M-cadherin promoter and bind the E4-box. PMID: 20334626
6. Mrf4 expression precedes or is contemporaneous with that of Myf5, suggesting that this transcription factor plays a hitherto unsuspected role in myogenesis PMID: 12204280
7. an enhancer element directs MRF4 gene expression primarily in fast muscle fibers PMID: 12435381
8. elements within a 7.5-kb promoter fragment of the MRF4 gene are sufficient to drive the embryonic wave of expression very similar to the endogenous gene in somites of mouse embryos PMID: 15282164
9. Expression of the Na(V) 1.4 Na+ channel was substantially reduced in MRF4-null mice, both in the surface membrane and at neuromuscular junctions. Thus, MRF4 appears to play a novel and selective role in adult muscle. PMID: 16358417
10. Taken together, these results indicate that MRF4 and MyoD play competitive roles in myogenesis by stimulating cell proliferation and differentiation, respectively. PMID: 17959144
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亞細胞定位：

Nucleus.
組織特異性：

Skeletal muscle.
數據庫鏈接：

KEGG: mmu:17878

STRING: 10090.ENSMUSP00000047529

UniGene: Mm.11