Recombinant Mouse Leukocyte antigen CD37 (Cd37), partial

中文名稱：

Recombinant Mouse Leukocyte antigen CD37(Cd37),partial
貨號：

CSB-YP713974MO1
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Leukocyte antigen CD37(Cd37),partial
貨號：

CSB-EP713974MO1
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Leukocyte antigen CD37(Cd37),partial
貨號：

CSB-EP713974MO1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Leukocyte antigen CD37(Cd37),partial
貨號：

CSB-BP713974MO1
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Leukocyte antigen CD37(Cd37),partial
貨號：

CSB-MP713974MO1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cd37
Uniprot No.：

Q61470
別名：

Cd37; Leukocyte antigen CD37; CD antigen CD37
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

基因功能參考文獻：
1. CD37 may protect against IgA nephropathy by inhibition of the IL-6 pathway. PMID: 29551516
2. this study identifies CD37 as a tumor suppressor that directly protects against B cell lymphomagenesis PMID: 26784544
3. The CD37-targeted antibody-drug conjugate IMGN529 is highly active against human CLL and in a novel CD37 transgenic murine leukemia model. PMID: 24445867
4. The cellular defect that underlies poor cellular immune induction in CD37-defcient mice is impaired dendritic cell migration. PMID: 23420539
5. CD37 was required for the mobility and clustering of alpha(4)beta(1) integrins in the plasma membrane, thus regulating the membrane distribution of alpha(4)beta(1) integrin necessary for activation of the Akt survival pathway PMID: 23150881
6. CD37 protects against glomerular IgA deposition and renal pathology PMID: 20348240
7. The influence of CD37 in the early events of T cell receptor signaling demonstrates a regulatory role for CD37 in T cell proliferation. PMID: 14978098
8. tetraspanin protein CD37 inhibits IgA responses and regulates the anti-fungal immune response. PMID: 19282981
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亞細胞定位：

Membrane; Multi-pass membrane protein.
蛋白家族：

Tetraspanin (TM4SF) family
數據庫鏈接：

KEGG: mmu:12493

STRING: 10090.ENSMUSP00000096061

UniGene: Mm.3689