Recombinant Mouse Intercellular adhesion molecule 4 (Icam4), partial

^{In
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中文名稱：

小鼠Icam4重組蛋白
品名簡稱：

Recombinant Mouse Icam4 protein, partial
貨號：

CSB-EP880644MO
說明書：

MSDS Datasheet
規(guī)格：

￥1836
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

Greater than 90% as determined by SDS-PAGE.
基因名：

Icam4
Uniprot No.：

Q9ERM2
別名：

Icam4; Intercellular adhesion molecule 4; ICAM-4; CD antigen CD242
種屬：

Mus musculus (Mouse)
蛋白長度：

Extracellular Domain
來源：

E.coli
分子量：

39.1kDa
表達(dá)區(qū)域：

23-231aa
氨基酸序列

QQEWMQSPPAPSVTSAPFWVRLNPELEAVPPGGSAWLNCSHNCPLPVHSSLRTQLRQGKIVNGSGWVSYQLLDVRAWNSKVRCVVTCAGETREATARITAYKRPRSVILEPPVLVGHKYTLRCYVTHVFPVGFLVVSLRRGGRVIYHESLERFTGSDLANVTLTYVMRAGLNDLWQPLTCHARLNLDGLVVRSSSAPVMLTVLALSPAS
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標(biāo)簽：

N-terminal 6xHis-SUMO-tagged
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
Note: If you have any special requirement for the glycerol content, please remark when you place the order.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Adhesion molecule that binds to leukocyte adhesion LFA-1 protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins. Isoform 2 may modulate binding of membrane-associated ICAM4.
基因功能參考文獻(xiàn)：
1. A novel second splice cDNA encodes an ICAM-4 isoform lacking the membrane-spanning domain. Erythroblasts express both isoforms. This new isoform, ICAM-4S, may modulate membrane-associated ICAM-4 binding & regulate erythroblast molecular attachments. PMID: 12406883
2. ICAM-4 is critical in erythroblastic island formation via ICAM-4/alpha(V) adhesion PMID: 16690966
亞細(xì)胞定位：

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
蛋白家族：

Immunoglobulin superfamily, ICAM family
數(shù)據(jù)庫鏈接：

KEGG: mmu:78369

STRING: 10090.ENSMUSP00000001040

UniGene: Mm.30220