Recombinant Mouse DEP domain-containing protein 5 (Depdc5), partial

中文名稱：

Recombinant Mouse DEP domain-containing protein 5(Depdc5) ,partial
貨號：

CSB-YP006728MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse DEP domain-containing protein 5(Depdc5) ,partial
貨號：

CSB-EP006728MO
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse DEP domain-containing protein 5(Depdc5) ,partial
貨號：

CSB-EP006728MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse DEP domain-containing protein 5(Depdc5) ,partial
貨號：

CSB-BP006728MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse DEP domain-containing protein 5(Depdc5) ,partial
貨號：

CSB-MP006728MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Depdc5
Uniprot No.：

P61460
別名：

Depdc5; Kiaa0645GATOR complex protein DEPDC5; DEP domain-containing protein 5
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway.
亞細胞定位：

Cytoplasm, cytosol. Cytoplasm, perinuclear region. Lysosome membrane.
蛋白家族：

IML1 family
組織特異性：

Expressed at low levels in all brain regions. Expressed throughout brain development, including in midgestation embryonic head (11.5 dpc), neonatal brain and whole adult brain. Present in neurons and absent in non-neuronal cells, including astrocytes (at
數據庫鏈接：

KEGG: mmu:277854

STRING: 10090.ENSMUSP00000113862

UniGene: Mm.101524