Recombinant Mouse Cytoplasmic FMR1-interacting protein 2 (Cyfip2), partial

中文名稱：

Recombinant Mouse Cytoplasmic FMR1-interacting protein 2(Cyfip2) ,partial
貨號：

CSB-YP735946MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cytoplasmic FMR1-interacting protein 2(Cyfip2) ,partial
貨號：

CSB-EP735946MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cytoplasmic FMR1-interacting protein 2(Cyfip2) ,partial
貨號：

CSB-EP735946MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cytoplasmic FMR1-interacting protein 2(Cyfip2) ,partial
貨號：

CSB-BP735946MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cytoplasmic FMR1-interacting protein 2(Cyfip2) ,partial
貨號：

CSB-MP735946MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cyfip2
Uniprot No.：

Q5SQX6
別名：

Cyfip2; Kiaa1168; Pir121Cytoplasmic FMR1-interacting protein 2; p53-inducible protein 121
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Involved in T-cell adhesion and p53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
基因功能參考文獻：
1. Study characterized the functional roles of the two brain-specific phosphorylation sites (S582 and T1067) of CYFIP2 in cultured hippocampal neurons; found that overexpression of the phospho-blocking T1067A mutant significantly decreased the density of stubby spines, but not other types of spines. Study found that T1067 phosphorylation of CYFIP2 could potentially weaken the interaction between CYFIP2 and Nap1. PMID: 28692454
2. Study identified cytoplasmic FMR1-Interacting Protein 2 (Cyfip2) as a major significant genetic factor underlying binge eating and provide a behavioral paradigm for future genome-wide association studies in populations with increased genetic complexity. PMID: 27914629
3. Study provides evidence for the role of Cyfip2 in fragile X-like behaviors and regulation of dendritic spines, and for the mGluR-induced regulation of Cyfip2 expression, which could provide new insight into the pathogenesis of the neurological fragile X syndrome phenotypes. PMID: 25432536
亞細胞定位：

Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell junction, synapse, synaptosome.
蛋白家族：

CYFIP family
組織特異性：

Expressed in hippocampus (at protein level).
數據庫鏈接：

KEGG: mmu:76884

STRING: 10090.ENSMUSP00000090853

UniGene: Mm.154358