Recombinant Mouse Cysteine-rich secretory protein 2 (Crisp2)

中文名稱：

Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2)
貨號：

CSB-YP005975MO
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2)
貨號：

CSB-EP005975MO
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2)
貨號：

CSB-EP005975MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2)
貨號：

CSB-BP005975MO
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Mouse Cysteine-rich secretory protein 2(Crisp2)
貨號：

CSB-MP005975MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Crisp2
Uniprot No.：

P16563
別名：

Crisp2; Tpx-1; Tpx1Cysteine-rich secretory protein 2; CRISP-2; Testis-specific protein TPX-1
種屬：

Mus musculus (Mouse)
蛋白長度：

Full Length of Mature Protein
表達區域：

23-243
氨基酸序列

KDPDFTSL LTNQLQVQRE IVNKHNELRR SVNPTGSDIL KMEWSIQATT NAQKWANKCI LEHSSKDDRK INIRCGENLY MSTDPTLWST VIQSWYNENE DFVYGVGAKP NSAVGHYTQL VWYSSFKIGC GIAYCPNQDN LKYFYVCHYC PMGNNVMKKS TPYQQGTPCA SCPNNCENGL CTNSCDFEDL LSNCESLKTS AGCKHELLKT KCQATCLCED KIH
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation.
基因功能參考文獻：
1. Crisp2 genetic defects in sperm from humans and mice result in male infertility. PMID: 26786179
2. expression and localization of SHTAP in testis and sperm raise the possibility that the SHTAP-CRISP2 complex has a potential role in sperm formation and/or function. PMID: 19686095
3. Tpx-1 Crisp domain on its own can regulate ion channel activity and provide compelling evidence for a role for Tpx-1 in the regulation of Ca(2+) fluxes observed during sperm capacitation. PMID: 16339766
4. Evidence for a functional role of CRISP2 in fertilization. PMID: 17202389
5. These data raise the possibility that CRISP2 is a MAP3K11-modifying protein or, alternatively, that MAP3K11 acts to phosphorylate CRISP2 during acrosome development. PMID: 17377140
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亞細胞定位：

Secreted.
蛋白家族：

CRISP family
組織特異性：

Testis.
數據庫鏈接：

KEGG: mmu:22024

STRING: 10090.ENSMUSP00000024724

UniGene: Mm.1296