Recombinant Liprin-alpha (syd-2), partial

中文名稱：

秀麗隱桿線蟲syd-2重組蛋白
貨號：

CSB-YP637407CXY
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲syd-2重組蛋白
貨號：

CSB-EP637407CXY
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲syd-2重組蛋白
貨號：

CSB-EP637407CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲syd-2重組蛋白
貨號：

CSB-BP637407CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲syd-2重組蛋白
貨號：

CSB-MP637407CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

syd-2
Uniprot No.：

Q21049
別名：

syd-2; F59F5.6Liprin-alpha; LAR-interacting protein alpha; Synapse defective protein 2
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play a role in regulating the structure of the neuronal region, called the active zone, from which synaptic vesicles send neurotransmitter signals across the synapse. This may be in association with the liprin-beta protein hlb-1.
基因功能參考文獻：
1. N-terminal CC domains are responsible for the synaptogenic activity of SYD-2. PMID: 23541703
2. A main role of SYD-2/Liprin-alpha in synaptogenesis is to regulate the polymerization of DPs. PMID: 24322429
3. tudy shows that SYD-2 promotes bi-directional mobility of DCVs and identifies SYD-2 as a novel regulator of DCV trafficking and polarized distribution PMID: 23358451
4. Loss of function in C. elegans syd-2 Liprin-alpha alters the size of presynaptic specializations and disrupts synaptic vesicle accumulationA missense mutation in the coiled-coil domain of SYD-2 causes a gain of function. PMID: 17115037
5. SYD-2, SYD-1 and UNC-10 were found essential for presynaptic site active zone assembly at synapses PMID: 19436057
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亞細胞定位：

Cell junction, synapse. Note=Presynaptic region.
蛋白家族：

Liprin family, Liprin-alpha subfamily
組織特異性：

Detected in vulval muscle and other cells near the vulva; in neurons located in the lateral ganglion, posterior ganglion, ventral cord and lateral body; and in pharyngeal and body wall muscle cells.
數據庫鏈接：

KEGG: cel:CELE_F59F5.6

STRING: 6239.F59F5.6

UniGene: Cel.19549