Recombinant Human X-ray radiation resistance-associated protein 1 (XRRA1)

中文名稱：

人XRRA1重組蛋白
貨號：

CSB-YP747397HU
規格：
來源：

Yeast
其他：

中文名稱：

人XRRA1重組蛋白
貨號：

CSB-EP747397HU
規格：
來源：

E.coli
其他：

中文名稱：

人XRRA1重組蛋白
貨號：

CSB-EP747397HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人XRRA1重組蛋白
貨號：

CSB-BP747397HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人XRRA1重組蛋白
貨號：

CSB-MP747397HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

XRRA1
Uniprot No.：

Q6P2D8
別名：

XRRA1; X-ray radiation resistance-associated protein 1
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-792
氨基酸序列

MAFSGIYKLD DGKPYLNNCF PARNLLRVPE EGQGHWLVVQ KGNLKKKPKG LVGAQAERRE SLKATSFEFK GKKESRRENQ VDLPGHILDQ AFLLKHHCVR KPSDLCTINA KENDFKHFHS VIYINASENL LPLEAFHTFP ALKELDLAFN GIKTIYVKYG DFKLLEFLDL SFNSLTVEAI CDLGILPHLR VLLLTGNGLT SLPPNLAVAE QEASVTSLTS KRYILRFPAL ETLMLDDNRL SNPSCFASLA GLRRLKKLSL DENRIIRIPY LQQVQLYDES VDWNGGRGSP HKEPQFMLQS KPRMLEDSDE QLDYTVLPMK KDVDRTEVVF SSYPGFSTSE TTKICSLPPI FEILPVKSLK ARNQTLAPPF PELRYLSLAY NKIAKEDAVL PVALFPSLCE FVFHNNPLVA HTRGVPPLLK SFLQERLGIH LIRRKIVKPK HHVLMSRKES WKVKSEIPKV PKQPLVLHHP RMTTTKSPSK DMLEPEAELA EDLPTTKSTS VESEMPTENL EGHSPSCRTF VPLPPICSNS TVHSEETLSH LSDTTVRLSP ERPSDEDSKS TESIFLTQVS ELPSSVIHKD DLELKEKDQK KPPTAPREVK GTRRKLPTAF LPSKYHGYEE LLTAKPDPAF IEPKGIQKNA QALQQMLKHP LLCHSSKPKL DTLQKPYVHK EKRAQRIPIP PPKKTRAQLL DDIFIRLRDP RNITEAPLGA VLHQWTERRL VNHKQYLEAK RLLKEFQARY RQLVSGSLRT VFGTTPLPMA CPALSESQPK FGHFLEFMDE FCQEPTASDS QG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May be involved in the response of cells to X-ray radiation.
基因功能參考文獻：
1. our results identify a novel link between XRRA1 and the ATM/CHK1/2 pathway and suggest that XRRA1 is involved in a DNA damage response that drives radio- and chemoresistance by regulating the ATM/CHK1/2 pathway. PMID: 29082250
2. Molecular cloning and gene expression patterns of XRRA1. PMID: 12908878
亞細胞定位：

Cytoplasm. Nucleus.
組織特異性：

Expressed predominantly in testis followed by prostate and ovary. Low levels found in other tissues including peripheral blood leukocytes, spleen, thymus, small intestine and colon. Also expressed in neuroblastoma, glioma, breast, lung, leukemia, renal, o
數據庫鏈接：

HGNC: 18868

OMIM: 609788

KEGG: hsa:143570

STRING: 9606.ENSP00000339918

UniGene: Hs.370145