Recombinant Human Testis-expressed sequence 11 protein (TEX11), partial

中文名稱：

人TEX11重組蛋白
貨號：

CSB-YP818259HU
規格：
來源：

Yeast
其他：

中文名稱：

人TEX11重組蛋白
貨號：

CSB-EP818259HU
規格：
來源：

E.coli
其他：

中文名稱：

人TEX11重組蛋白
貨號：

CSB-EP818259HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人TEX11重組蛋白
貨號：

CSB-BP818259HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人TEX11重組蛋白
貨號：

CSB-MP818259HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TEX11
Uniprot No.：

Q8IYF3
別名：

TEX11; Testis-expressed protein 11
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
基因功能參考文獻：
1. Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility. PMID: 28364521
2. Genetic screening of a large cohort of idiopathic infertile men reveals that TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of azoospermic men. PMID: 26136358
3. TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of non-obstructive azoospermic men. PMID: 26136358
4. hemizygous TEX11 mutations were a common cause of meiotic arrest and azoospermia in infertile men PMID: 25970010
5. TEX11 was specifically expressed in human testis. PMID: 11279525
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相關疾病：

Spermatogenic failure, X-linked, 2 (SPGFX2)
亞細胞定位：

Chromosome.
蛋白家族：

SPO22 family
組織特異性：

Testis-specific. Not expressed in adult ovaries.
數據庫鏈接：

HGNC: 11733

OMIM: 300311

KEGG: hsa:56159

STRING: 9606.ENSP00000340995

UniGene: Hs.121776