Recombinant Human Sodium/potassium-transporting ATPase subunit alpha-4 (ATP1A4), partial

中文名稱：

Recombinant Human Sodium/potassium-transporting ATPase subunit alpha-4(ATP1A4) ,partial
貨號：

CSB-YP619791HU
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Sodium/potassium-transporting ATPase subunit alpha-4(ATP1A4) ,partial
貨號：

CSB-EP619791HU
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Sodium/potassium-transporting ATPase subunit alpha-4(ATP1A4) ,partial
貨號：

CSB-EP619791HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Sodium/potassium-transporting ATPase subunit alpha-4(ATP1A4) ,partial
貨號：

CSB-BP619791HU
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Sodium/potassium-transporting ATPase subunit alpha-4(ATP1A4) ,partial
貨號：

CSB-MP619791HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ATP1A4
Uniprot No.：

Q13733
別名：

ATP1A4; ATP1AL2Sodium/potassium-transporting ATPase subunit alpha-4; Na(+)/K(+) ATPase alpha-4 subunit; EC 7.2.2.13; Sodium pump subunit alpha-4
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.
基因功能參考文獻：
1. Human ATP1A4 enhances mouse sperm motility and hyperactivity during capacitation. PMID: 25640246
2. Human Na,K-ATPase alpha 4 isoform is a sperm-specific protein localized to the flagellum, suggesting a role for human Na,K-ATPase alpha 4 isoform in human sperm physiology. PMID: 16175638
3. These results constitute the first demonstration of the transcriptional control of ATP1A4 gene expression by cAMP and by CREMtau, a transcription factor essential for male germ cell gene expression. PMID: 16894555
亞細胞定位：

Cell membrane; Multi-pass membrane protein. Note=In mature sperm, located in the principle piece of the sperm flagellum.
蛋白家族：

Cation transport ATPase (P-type) (TC 3.A.3) family, Type IIC subfamily
組織特異性：

Specifically expressed in testis. Found in very low levels in skeletal muscle. Expressed in mature sperm (at protein level).
數據庫鏈接：

HGNC: 14073

OMIM: 607321

KEGG: hsa:480

STRING: 9606.ENSP00000357060

UniGene: Hs.662219