Recombinant Human Protein phosphatase Slingshot homolog 2 (SSH2), partial

中文名稱：

人SSH2重組蛋白
貨號：

CSB-YP765732HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人SSH2重組蛋白
貨號：

CSB-EP765732HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人SSH2重組蛋白
貨號：

CSB-EP765732HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SSH2重組蛋白
貨號：

CSB-BP765732HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人SSH2重組蛋白
貨號：

CSB-MP765732HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SSH2
Uniprot No.：

Q76I76
別名：

hSSH 2L; hSSH-2L; KIAA1725; MGC78588; OTTHUMP00000163634; OTTHUMP00000163635; Protein phosphatase Slingshot homolog 2; Slingshot 2; Slingshot homolog 2 (Drosophila); Slingshot homolog 2; Slingshot2; SSH 2; SSH 2L; SSH-2L; SSH-like protein 2; SSH2; SSH2_HUMAN; SSH2L
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
基因功能參考文獻：
1. Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, PKCbeta and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified. PMID: 25568344
2. data indicate that: (a) apoptotic cell death in FLCN-null cells can be triggered by SSH2 knockdown through cell cycle arrest; (b) SSH2 represents a potential therapeutic target for the development of agents for the treatment of BHD syndrome related tumors PMID: 23416984
亞細胞定位：

Cytoplasm, cytoskeleton.
蛋白家族：

Protein-tyrosine phosphatase family
數據庫鏈接：

HGNC: 30580

OMIM: 606779

KEGG: hsa:85464

STRING: 9606.ENSP00000269033

UniGene: Hs.654754