Recombinant Human Protein FAM89B (FAM89B)

中文名稱：

人FAM89B重組蛋白
貨號：

CSB-YP854045HU
規格：
來源：

Yeast
其他：

中文名稱：

人FAM89B重組蛋白
貨號：

CSB-EP854045HU
規格：
來源：

E.coli
其他：

中文名稱：

人FAM89B重組蛋白
貨號：

CSB-EP854045HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FAM89B重組蛋白
貨號：

CSB-BP854045HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人FAM89B重組蛋白
貨號：

CSB-MP854045HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FAM89B
Uniprot No.：

Q8N5H3
別名：

FAM89B; Lrap25; Leucine repeat adapter protein 25
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-189
氨基酸序列

MNGLPSAEAP GGAGCALAGL PPLPRGLSGL LNASGGSWRE LERVYSQRSR IHDELSRAAR APDGPRHAAG AANAGPAAGP RRPVNLDSAL AALRKEMVGL RQLDMSLLCQ LWGLYESIQD YKHLCQDLSF CQDLSSSLHS DSSYPPDAGL SDDEEPPDAS LPPDPPPLTV PQTHNARDQW LQDAFHISL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Negatively regulates TGF-beta-induced signaling; in cooperation with SKI prevents the translocation of SMAD2 from the nucleus to the cytoplasm in response to TGF-beta. Acts as an adapter that mediates the specific recognition of LIMK1 by CDC42BPA and CDC42BPB in the lamellipodia. LRAP25-mediated CDC42BPA/CDC42BPB targeting to LIMK1 and the lamellipodium results in LIMK1 activation and the subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation.
基因功能參考文獻：
1. the functional relevance of the LRAP25-MRCK complex in LIMK1-cofilin signaling and the importance of LRAP adaptors as key determinants of MRCK cellular localization and downstream specificities. PMID: 25107909
2. identified two human genes, Mtvr1 and Mtvr2, encoding proteins highly related to the Mouse Mammary Tumor Virus receptor [Mtvr1] [Mtvr2] PMID: 11958456
亞細胞定位：

[Isoform 3]: Cytoplasm. Cell projection, lamellipodium.
蛋白家族：

FAM89 family
數據庫鏈接：

HGNC: 16708

OMIM: 616128

KEGG: hsa:23625

UniGene: Hs.731854