Recombinant Human Terminal nucleotidyltransferase 5A (TENT5A)

中文名稱：

人FAM46A重組蛋白
貨號：

CSB-YP822229HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人FAM46A重組蛋白
貨號：

CSB-EP822229HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人FAM46A重組蛋白
貨號：

CSB-EP822229HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FAM46A重組蛋白
貨號：

CSB-BP822229HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人FAM46A重組蛋白
貨號：

CSB-MP822229HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

TENT5A
Uniprot No.：

Q96IP4
別名：

Terminal nucleotidyltransferase 5A; EC:2.7.7.19; HBV X-transactivated gene 11 protein; HBV XAg-transactivated protein; TENT5A;C6orf37; FAM46A; XTP11
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-442aa
氨基酸序列

MAEGEGYFAM SEDELACSPY IPLGGDFGGG DFGGGDFGGG DFGGGGSFGG HCLDYCESPT AHCNVLNWEQ VQRLDGILSE TIPIHGRGNF PTLELQPSLI VKVVRRRLAE KRIGVRDVRL NGSAASHVLH QDSGLGYKDL DLIFCADLRG EGEFQTVKDV VLDCLLDFLP EGVNKEKITP LTLKEAYVQK MVKVCNDSDR WSLISLSNNS GKNVELKFVD SLRRQFEFSV DSFQIKLDSL LLFYECSENP MTETFHPTII GESVYGDFQE AFDHLCNKII ATRNPEEIRG GGLLKYCNLL VRGFRPASDE IKTLQRYMCS RFFIDFSDIG EQQRKLESYL QNHFVGLEDR KYEYLMTLHG VVNESTVCLM GHERRQTLNL ITMLAIRVLA DQNVIPNVAN VTCYYQPAPY VADANFSNYY IAQVQPVFTC QQQTYSTWLP CN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable nucleotidyltransferase that may act as a non-canonical poly(A) RNA polymerase.
基因功能參考文獻：
1. By functional analysis based on a set of 1129 proteins from 494 obese subjects study identified and validated FAM46A as a trans regulator for leptin. PMID: 29234017
2. This exploratory genome-wide association studies confirmed APOE and identified the novel loci: rs72907046 near FAM46A (P = 1 x 10(-9) OR = 3.2 [2.1-4.9]). PMID: 26993346
3. VNTR in the coding region of the FAM46A gene, FAM46A rs11040 SNP and BAG6 rs3117582 SNP are associated with susceptibility to tuberculosis PMID: 24625963
4. Genotype frequencies of cd (four and five VNTR repeats) and cc (four VNTR repeats homozygote) of the FAM46A gene were significantly decreased in the patients compared to the healthy controls in the Croatian and Norwegian subjects PMID: 25884493
5. Susceptibility to large-joint osteoarthritis (hip and knee) is associated with BAG6 rs3117582 SNP and the VNTR polymorphism in the second exon of the FAM46A gene on chromosome 6. PMID: 25231575
6. a candidate of human retinal disease on chromosome 6 PMID: 12054608
7. A novel VNTR polymorphism in C6orf37 exists in Chinese population and is not associated with colorectal cancer risk PMID: 16545789
8. Genetic analysis of FAM46A in Spanish families with autosomal recessive retinitis pigmentosa: characterization of novel VNTRs is reported. PMID: 17803723
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蛋白家族：

FAM46 family
組織特異性：

Widely expressed, with preferential expression observed in the retina compared to other ocular tissues. Also expressed in osteoblasts.
數據庫鏈接：

HGNC: 18345

OMIM: 611357

KEGG: hsa:55603

STRING: 9606.ENSP00000318298

UniGene: Hs.10784