Recombinant Human Phospholipid scramblase 4 (PLSCR4), partial

中文名稱：

人PLSCR4重組蛋白
貨號：

CSB-YP018210HU
規格：
來源：

Yeast
其他：

中文名稱：

人PLSCR4重組蛋白
貨號：

CSB-EP018210HU
規格：
來源：

E.coli
其他：

中文名稱：

人PLSCR4重組蛋白
貨號：

CSB-EP018210HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PLSCR4重組蛋白
貨號：

CSB-BP018210HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人PLSCR4重組蛋白
貨號：

CSB-MP018210HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PLSCR4
Uniprot No.：

Q9NRQ2
別名：

AV245873; Ca(2+)-dependent phospholipid scramblase 4; Cell growth inhibiting protein 43; Cell growth-inhibiting gene 43 protein; GIG43; Phospholipid scramblase 4; PL scramblase 4; Pls4; PLS4_HUMAN; Plscr4; TRA1
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
基因功能參考文獻：
1. the first report on the transcriptional regulation of hPLSCR4, where Snail was shown to downregulate the expression of Human phospholipid scramblase 4 PMID: 27363667
2. biochemical and functional characterization of human phospholipid scramblase 4 PMID: 23089641
3. Crystallographic analysis of mammalian importin alpha1 in complex with the hPLSCR4-NLS reveals this minimal NLS binds specifically and exclusively to the minor binding site of importin alpha PMID: 21690087
4. SLPI is a ligand for PLSCR1 and PLSCR4, which also interact directly with the CD4 receptor at the cell surface of T lymphocytes PMID: 19333378
亞細胞定位：

Membrane; Single-pass type II membrane protein.
蛋白家族：

Phospholipid scramblase family
組織特異性：

Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes.
數據庫鏈接：

HGNC: 16497

OMIM: 607612

KEGG: hsa:57088

STRING: 9606.ENSP00000347038

UniGene: Hs.477869