Recombinant Human Oviduct-specific glycoprotein (OVGP1)

中文名稱：

人OVGP1重組蛋白
貨號：

CSB-YP614260HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人OVGP1重組蛋白
貨號：

CSB-EP614260HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人OVGP1重組蛋白
貨號：

CSB-EP614260HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人OVGP1重組蛋白
貨號：

CSB-BP614260HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人OVGP1重組蛋白
貨號：

CSB-MP614260HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

OVGP1
Uniprot No.：

Q12889
別名：

CHIT5 ; EGP ; Estrogen dependent oviduct protein; Estrogen-dependent oviduct protein; MUC9 ; mucin 9 ; Mucin-9; OGP ; OVGP 9; Ovgp1; OVGP1_HUMAN; Oviduct glycoprotein; Oviduct-specific glycoprotein; Oviductal glycoprotein; Oviductin
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

22-678
氨基酸序列

HKLVCYFTN WAHSRPGPAS ILPHDLDPFL CTHLIFAFAS MNNNQIVAKD LQDEKILYPE FNKLKERNRE LKTLLSIGGW NFGTSRFTTM LSTFANREKF IASVISLLRT HDFDGLDLFF LYPGLRGSPM HDRWTFLFLI EELLFAFRKE ALLTMRPRLL LSAAVSGVPH IVQTSYDVRF LGRLLDFINV LSYDLHGSWE RFTGHNSPLF SLPEDPKSSA YAMNYWRKLG APSEKLIMGI PTYGRTFRLL KASKNGLQAR AIGPASPGKY TKQEGFLAYF EICSFVWGAK KHWIDYQYVP YANKGKEWVG YDNAISFSYK AWFIRREHFG GAMVWTLDMD DVRGTFCGTG PFPLVYVLND ILVRAEFSST SLPQFWLSSA VNSSSTDPER LAVTTAWTTD SKILPPGGEA GVTEIHGKCE NMTITPRGTT VTPTKETVSL GKHTVALGEK TEITGAMTMT SVGHQSMTPG EKALTPVGHQ SVTTGQKTLT SVGYQSVTPG EKTLTPVGHQ SVTPVSHQSV SPGGTTMTPV HFQTETLRQN TVAPRRKAVA REKVTVPSRN ISVTPEGQTM PLRGENLTSE VGTHPRMGNL GLQMEAENRM MLSSSPVIQL PEQTPLAFDN RFVPIYGNHS SVNSVTPQTS PLSLKKEIPE NSAVDEEA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
基因功能參考文獻：
1. OVGP1 is specifically induced in the luminal epithelium at the time of embryo implantation where it regulates receptivity-related genes and aids in trophoblast adhesion. PMID: 29968069
2. Decreased gene expression of MUC9 was found from colonic biopsies in patients with active and remission ulcerative colitis. PMID: 22028245
3. OVGP1 seems to detect a different spectrum of ovarian epithelial cancers than other markers and thus should be a useful adjunct for more accurate detection, particularly of early serous ovarian cancers and mucinous carcinomas. PMID: 20130498
4. cloning and characterization of the promoter and gene expression regulation in the oviduct (human oviduct-specific glycoprotein, HuOPG) PMID: 11818519
5. The production and function of oviductin at different stages of human reproductive cycle is not well known. Its highest expression at the time of ovulation is consistent with a supportive role in fertilization and early embryo development. PMID: 12503889
6. Gain of oviduct-specific glycoprotein is associated with the development of endometrial hyperplasia and endometrial cancer PMID: 15585630
7. The presence of oviductin mRNA and protein has been determined in OE-E6/E7, an immortalized human oviductal epithelial cell line. PMID: 16209999
8. Results suggests the binding of OGP to human sperm mediates through MYH9. PMID: 16567366
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亞細胞定位：

Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
蛋白家族：

Glycosyl hydrolase 18 family
組織特異性：

Oviduct.
數據庫鏈接：

HGNC: 8524

OMIM: 603578

KEGG: hsa:5016

STRING: 9606.ENSP00000358747

UniGene: Hs.1154