Recombinant Human Neuroligin-4, Y-linked (NLGN4Y), partial

中文名稱：

人NLGN4Y重組蛋白
貨號：

CSB-YP818786HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人NLGN4Y重組蛋白
貨號：

CSB-EP818786HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人NLGN4Y重組蛋白
貨號：

CSB-EP818786HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人NLGN4Y重組蛋白
貨號：

CSB-BP818786HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人NLGN4Y重組蛋白
貨號：

CSB-MP818786HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

NLGN4Y
Uniprot No.：

Q8NFZ3
別名：

ASPGX2; AUTSX2; HGNC:14287; HLNX; HNLX; KIAA0951; KIAA1260; MGC22376; Neuroligin 4 X linked ; Neuroligin 4, Y linked; Neuroligin X; Neuroligin Y; Neuroligin-4; NLGN; NLGN4; NLGN4X; NLGN4Y; NLGNY_HUMAN; Y-linked
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Putative neuronal cell surface protein involved in cell-cell-interactions.
基因功能參考文獻：
1. Results suggest an association between a maternal immune response to neuroligin 4 Y-linked (NLGN4Y) and subsequent sexual orientation in male offspring. PMID: 29229842
2. Results suggest that NLGN4Y is an important negative regulator in prostate cancer progression. PMID: 27626693
3. Expression of NLGN4Y, a gene that may be involved in synaptic function, is increased in boys with XYY PMID: 25558953
4. investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism PMID: 19605777
5. Neuroligin mutations most probably represent rare causes of autism; it is unlikely that the allelic variants in any of these genes would be major risk factors for autism. PMID: 16077734
6. The coding sequences and splice junctions of the NLGN4Y gene were analyzed in 335 male samples (290 with autism and 45 with mental retardation) to analyze sequence variants in NLGN4Y that are associated with autism or mental retardation. PMID: 18628683
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亞細胞定位：

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane.
蛋白家族：

Type-B carboxylesterase/lipase family
組織特異性：

Expressed in fetal and adult brain, prostate and testis.
數據庫鏈接：

HGNC: 15529

OMIM: 400028

KEGG: hsa:22829

STRING: 9606.ENSP00000342535

UniGene: Hs.439199