Recombinant Human Mucin-3A (MUC3A), partial

中文名稱：

人MUC3A重組蛋白
貨號(hào)：

CSB-YP015225HU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

人MUC3A重組蛋白
貨號(hào)：

CSB-EP015225HU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

人MUC3A重組蛋白
貨號(hào)：

CSB-EP015225HU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MUC3A重組蛋白
貨號(hào)：

CSB-BP015225HU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

人MUC3A重組蛋白
貨號(hào)：

CSB-MP015225HU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

MUC3A
Uniprot No.：

Q02505
別名：

MUC3A; MUC3; Mucin-3A; MUC-3A; Intestinal mucin-3A
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.
基因功能參考文獻(xiàn)：
1. MUC3A may have a role in poor prognosis in localized clear-cell renal cell carcinoma PMID: 27374181
2. DNA hypomethylation in the 5'-flanking region of the MUC3A gene plays an important role in MUC3A expression in carcinomas of various organs. PMID: 20510874
3. has highly conserved amino and carboxyl termini, suggesting a recent duplication of the entire ancestral gene PMID: 12958310
4. MUC3 is overexpressed in renal clear cell carcinoma, and the MUC3 expression ratio is greater in nuclear grade 3 than in grades 1 and 2 (low grades) tumor. These findings suggest the implication of MUC3 in renal carcinogenesis. PMID: 14550470
5. up-regulated MUC expression by synovial tissue cells and suggest a novel role of MUC3 and MUC5AC in the pathogenesis of arthritis PMID: 18163520
6. We report the colonic adhesion mechanism of Lactobaillus plantarums LA318 is in part due to GAPDH binding to human ABO-type blood group antigens expressed on human colonic mucin (HCM). [HCM] PMID: 18790050
7. Data show that the diagnostic sensitivity for mucin was 60%, and the specificity for mucin was 100%. PMID: 19365834
8. Data show that special stains for mucin did not distinguish pseudocysts from neoplastic mucinous cysts. PMID: 19365837
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亞細(xì)胞定位：

[Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.
組織特異性：

Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 7513

OMIM: 158371

KEGG: hsa:4584

STRING: 9606.ENSP00000324834

UniGene: Hs.703577