Recombinant Human GSK-3-binding protein FRAT2 (FRAT2)

中文名稱：

人FRAT2重組蛋白
貨號：

CSB-YP008971HU
規格：
來源：

Yeast
其他：

中文名稱：

人FRAT2重組蛋白
貨號：

CSB-EP008971HU
規格：
來源：

E.coli
其他：

中文名稱：

人FRAT2重組蛋白
貨號：

CSB-EP008971HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FRAT2重組蛋白
貨號：

CSB-BP008971HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人FRAT2重組蛋白
貨號：

CSB-MP008971HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FRAT2
Uniprot No.：

O75474
別名：

FRAT2GSK-3-binding protein FRAT2; Frequently rearranged in advanced T-cell lymphomas 2; FRAT-2
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-233
氨基酸序列

MPCRREEEEE AGEEAEGEEE EDDSFLLLQQ SVTLGSSGEV DRLVAQIGET LQLDAAQDSP ASPCAPPGVP LRAPGPLAAA VPADKARPPA VPLLLPPASA ETVGPAPSGA LRCALGDRGR VRGRAAPYCV AEVAAGPSAL PGPCRRGWLR DAVTSRRLQQ RRWTQAGARA GDDDPHRLLQ QLVLSGNLIK EAVRRLQRAV AAVAATGPAS APGPGGGRSG PDRIALQPSG SLL
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.
基因功能參考文獻：
1. FRAT-2 enhances glycogen synthase kinase 3 beta-mediated phosphorylation of a primed substrate to a greater extent than an unprimed substrate PMID: 15522877
2. It suggests that activation of GSK-3 inhibits PP-2A through up-regulation of I(2)(PP-2A) with hnRNP A18-involved mechanism. PMID: 17433504
蛋白家族：

GSK-3-binding protein family
數據庫鏈接：

HGNC: 16048

OMIM: 605006

KEGG: hsa:23401

STRING: 9606.ENSP00000360058

UniGene: Hs.140720