Recombinant Human Lipid transferase CIDEB (CIDEB)

中文名稱：

Recombinant Human Lipid transferase CIDEB(CIDEB)
貨號：

CSB-YP887032HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Lipid transferase CIDEB(CIDEB)
貨號：

CSB-EP887032HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Lipid transferase CIDEB(CIDEB)
貨號：

CSB-EP887032HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Lipid transferase CIDEB(CIDEB)
貨號：

CSB-BP887032HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Lipid transferase CIDEB(CIDEB)
貨號：

CSB-MP887032HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CIDEB
Uniprot No.：

Q9UHD4
別名：

Cell death activator CIDE B; Cell death activator CIDE-B; Cell death inducing DFFA like effector B ; Cell death-inducing DFFA-like effector B; CIDEB; CIDEB_HUMAN
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-219
氨基酸序列

MEYLSALNPS DLLRSVSNIS SEFGRRVWTS APPPQRPFRV CDHKRTIRKG LTAATRQELL AKALETLLLN GVLTLVLEED GTAVDSEDFF QLLEDDTCLM VLQSGQSWSP TRSGVLSYGL GRERPKHSKD IARFTFDVYK QNPRDLFGSL NVKATFYGLY SMSCDFQGLG PKKVLRELLR WTSTLLQGLG HMLLGISSTL RHAVEGAEQW QQKGRLHSY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Activates apoptosis.; (Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.
基因功能參考文獻：
1. High Cideb expression is associated with Ulcerative Colitis. PMID: 28719542
2. CIDEB interacts with the HCV NS5A protein, and the N terminus of CIDEB and the domain I of NS5A are involved in this interaction. PMID: 27282740
3. these data revealed that Cideb plays an important role in controlling intestinal chylomicron lipidation. PMID: 24831470
4. this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB PMID: 27213693
5. CIDEB downregulation may contribute to HCV-induced hepatic steatosis PMID: 26865724
6. CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis. PMID: 24980280
7. Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes. PMID: 24829338
8. this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha/CIDEB pathway's role in LD dynamics and the VLDL pathway. PMID: 24161736
9. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma. PMID: 23475172
10. A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported. PMID: 16248853
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組織特異性：

Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen.
數(shù)據(jù)庫鏈接：

HGNC: 1977

OMIM: 604441

KEGG: hsa:27141

STRING: 9606.ENSP00000258807

UniGene: Hs.642693