Recombinant Human Cationic amino acid transporter 3 (SLC7A3), partial

中文名稱：

人SLC7A3重組蛋白
貨號：

CSB-YP855505HU
規格：
來源：

Yeast
其他：

中文名稱：

人SLC7A3重組蛋白
貨號：

CSB-EP855505HU
規格：
來源：

E.coli
其他：

中文名稱：

人SLC7A3重組蛋白
貨號：

CSB-EP855505HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SLC7A3重組蛋白
貨號：

CSB-BP855505HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人SLC7A3重組蛋白
貨號：

CSB-MP855505HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SLC7A3
Uniprot No.：

Q8WY07
別名：

SLC7A3; ATRC3; CAT3; Cationic amino acid transporter 3; CAT-3; CAT3; Cationic amino acid transporter y+; Solute carrier family 7 member 3
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.
基因功能參考文獻：
1. rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors PMID: 26215737
2. knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells PMID: 25130427
3. CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution. PMID: 22870827
4. is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg. PMID: 15737334
5. It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane. PMID: 16332251
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family
組織特異性：

Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.
數據庫鏈接：

HGNC: 11061

OMIM: 300443

KEGG: hsa:84889

STRING: 9606.ENSP00000298085

UniGene: Hs.175220