Recombinant Human Acyl-protein thioesterase 2 (LYPLA2)

中文名稱：

人LYPLA2重組蛋白
貨號：

CSB-YP013269HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人LYPLA2重組蛋白
貨號：

CSB-EP013269HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人LYPLA2重組蛋白
貨號：

CSB-EP013269HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人LYPLA2重組蛋白
貨號：

CSB-BP013269HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人LYPLA2重組蛋白
貨號：

CSB-MP013269HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LYPLA2
Uniprot No.：

O95372
別名：

Acyl protein thioesterase 2; Acyl protein thioesterase; Acyl-protein thioesterase 2; APT 2; APT-2; APT2; DJ886K2.4; EC 3.1.2.- ; LPL I; LPL II; LPL-II; LYPA2_HUMAN; LYPLA 2; Lypla2; Lysophospholipase II; LysoPLA II; OTTHUMP00000002999; OTTHUMP00000044831
種屬：

Homo sapiens (Human)
蛋白長度：

Full length protein
表達區域：

1-231
氨基酸序列

MCGNTMSVPL LTDAATVSGA ERETAAVIFL HGLGDTGHSW ADALSTIRLP HVKYICPHAP RIPVTLNMKM VMPSWFDLMG LSPDAPEDEA GIKKAAENIK ALIEHEMKNG IPANRIVLGG FSQGGALSLY TALTCPHPLA GIVALSCWLP LHRAFPQAAN GSAKDLAILQ CHGELDPMVP VRFGALTAEK LRSVVTPARV QFKTYPGVMH SSCPQEMAAV KEFLEKLLPP V
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G). Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide.
基因功能參考文獻：
1. LYPLA2 is the major prostaglandin glycerol ester hydrolase in human cancer cells. PMID: 25301951
2. Results demonstrate that APT-2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. PMID: 21152083
亞細胞定位：

Cytoplasm.
蛋白家族：

AB hydrolase superfamily, AB hydrolase 2 family
組織特異性：

Expressed in various breast cancer cell lines.
數據庫鏈接：

HGNC: 6738

KEGG: hsa:11313

STRING: 9606.ENSP00000363638

UniGene: Hs.533479