Recombinant Human 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (PFKFB1)

中文名稱：

人PFKFB1重組蛋白
貨號：

CSB-YP017817HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人PFKFB1重組蛋白
貨號：

CSB-EP017817HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人PFKFB1重組蛋白
貨號：

CSB-EP017817HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人PFKFB1重組蛋白
貨號：

CSB-BP017817HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人PFKFB1重組蛋白
貨號：

CSB-MP017817HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PFKFB1
Uniprot No.：

P16118
別名：

6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 1; 6-bisphosphatase; 6-P2ase 1; 6-P2ASE liver isozyme; 6PF 2 K/Fru 2 6 P2ASE liver isozyme; 6PF 2 K/Fru 2,6 P2ase 1; 6PF-2-K/Fru-2; F261_HUMAN; F6PK; Fructose 2 6 bisphosphatase; Fructose 6 phosphate 2 kinase:fructose 2 6 bisphosphatase; Fructose-2; HL2K; MGC116715; MGC116717; PFK/FBPase 1; PFKFB 1; Pfkfb1; PFRX
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-471
氨基酸序列

SPEMGELTQ TRLQKIWIPH SSGSSRLQRR RGSSIPQFTN SPTMVIMVGL PARGKTYIST KLTRYLNWIG TPTKVFNLGQ YRREAVSYKN YEFFLPDNME ALQIRKQCAL AALKDVHNYL SHEEGHVAVF DATNTTRERR SLILQFAKEH GYKVFFIESI CNDPGIIAEN IRQVKLGSPD YIDCDREKVL EDFLKRIECY EVNYQPLDEE LDSHLSYIKI FDVGTRYMVN RVQDHIQSRT VYYLMNIHVT PRSIYLCRHG ESELNIRGRI GGDSGLSVRG KQYAYALANF IQSQGISSLK VWTSHMKRTI QTAEALGVPY EQWKALNEID AGVCEEMTYE EIQEHYPEEF ALRDQDKYRY RYPKGESYED LVQRLEPVIM ELERQENVLV ICHQAVMRCL LAYFLDKSSD ELPYLKCPLH TVLKLTPVAY GCKVESIYLN VEAVNTHREK PENVDITREP EEALDTVPAH Y
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Synthesis and degradation of fructose 2,6-bisphosphate.
基因功能參考文獻：
1. Insulin resistance in obese boys leads to up-regulation of INSIG2 gene expression as well as to down-regulation of PFKFB1, PFKFB3, and HK2 genes in the blood cells as compared to obese patients with normal insulin sensitivity. PMID: 26827442
2. Results describe structural differences between two isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from liver and testis. PMID: 12379646
蛋白家族：

Phosphoglycerate mutase family
組織特異性：

Liver.
數據庫鏈接：

HGNC: 8872

OMIM: 311790

KEGG: hsa:5207

STRING: 9606.ENSP00000364145

UniGene: Hs.444304