Recombinant Drosophila melanogaster Cullin homolog 1 (lin19), partial

中文名稱：

Recombinant Drosophila melanogaster Cullin homolog 1(lin19) ,partial
貨號(hào)：

CSB-YP638760DLU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Drosophila melanogaster Cullin homolog 1(lin19) ,partial
貨號(hào)：

CSB-EP638760DLU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Drosophila melanogaster Cullin homolog 1(lin19) ,partial
貨號(hào)：

CSB-EP638760DLU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Drosophila melanogaster Cullin homolog 1(lin19) ,partial
貨號(hào)：

CSB-BP638760DLU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Drosophila melanogaster Cullin homolog 1(lin19) ,partial
貨號(hào)：

CSB-MP638760DLU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Cul1
Uniprot No.：

Q24311
別名：

Cul1; cul-1; lin19; CG1877Cullin homolog 1; Lin-19 homolog protein
種屬：

Drosophila melanogaster (Fruit fly)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larval ddaC dendrites and mushroom body axons. The SCF-slmb complex also regulates asymmetrical division of neuroblasts and inhibits ectopic neuroblast formation partly through SAK and Akt1. Also part of an SCF complex required for caspase activation during sperm differentiation. Necessary for auditory transduction: plays a role in Johnston's organ organization by acting in the regulation of zip and ck function in scolopidial apical attachment. May function by acting in a Ubr3-mediated pathway that negatively regulates the ubiquitination of zip, consequently affecting its interaction with ck.
亞細(xì)胞定位：

Cytoplasm. Note=In the spermatid, colocalizes with ntc at the actin-based individualization complex and the cystic bulge.
蛋白家族：

Cullin family
組織特異性：

Expressed in testis.
數(shù)據(jù)庫(kù)鏈接：

KEGG: dme:Dmel_CG1877

STRING: 7227.FBpp0087921

UniGene: Dm.7926