Recombinant Cullin-4 (cul-4), partial

中文名稱：

Recombinant Cullin-4(cul-4) ,partial
貨號：

CSB-YP621026CXY
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Cullin-4(cul-4) ,partial
貨號：

CSB-EP621026CXY
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Cullin-4(cul-4) ,partial
貨號：

CSB-EP621026CXY-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Cullin-4(cul-4) ,partial
貨號：

CSB-BP621026CXY
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Cullin-4(cul-4) ,partial
貨號：

CSB-MP621026CXY
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

cul-4
Uniprot No.：

Q17392
別名：

cul-4; F45E12.3Cullin-4; CUL-4
種屬：

Caenorhabditis elegans
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Component of cullin-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. In association with ddb-1 directs ubiquitination of cdt-1 during S phase and is required for restraining DNA rereplication. Probably is involved in ubiquitination of cki-1.
基因功能參考文獻：
1. proposal that CUL-4 prevents aberrant re-initiation of DNA replication, at least in part, by facilitating the degradation of CDT-1 PMID: 12815436
2. CUL-4 has a role in preventing rereplication by promoting the phosphorylation and subsequent translocation of CDC-6 from the nucleus during S phase. PMID: 17509881
蛋白家族：

Cullin family
數(shù)據(jù)庫鏈接：

KEGG: cel:CELE_F45E12.3

STRING: 6239.F45E12.3

UniGene: Cel.15594