Recombinant Chicken Interferon type B (IFNB)

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中文名稱：

雞IFNB重組蛋白
品名簡稱：

Recombinant Chicken IFNB protein
貨號：

CSB-EP838568CH
說明書：

MSDS Datasheet
規格：

￥1836
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
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靶點詳情

產品詳情

純度：

Greater than 85% as determined by SDS-PAGE.
基因名：

IFNB
Uniprot No.：

Q90873
別名：

IFNB; IFN2; Interferon type B; IFN-beta
種屬：

Gallus gallus (Chicken)
蛋白長度：

Full Length of Mature Protein
來源：

E.coli
分子量：

24.8 kDa
表達區域：

28-203aa
氨基酸序列

CNHLRHQDANFSWKSLQLLQNTAPPPPQPCPQQDVTFPFPETLLKSKDKKQAAITTLRILQHLFNMLSSPHTPKHWIDRTRHSLLNQIQHYIHHLEQCFVNQGTRSQRRGPRNAHLSINKYFRSIHNFLQHNNYSACTWDHVRLQARDCFRHVDTLIQWMKSRAPLTASSKRLNTQ
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Tris-based buffer,50% glycerol
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
產品描述：

This recombinant Chicken IFNB protein is an E.coli-expressed protein (Full Length of Mature Protein). At the theoretical level, the steps needed for obtaining a recombinant protein are pretty straightforward. Obtain the IFNB gene, clone it in an expression vector, transform it into the host of choice, induce it, and then, the protein is ready for purification and characterization. In practice, however, dozens of things can go wrong. Poor growth of the host, inclusion body formation, protein inactivity, and even not obtaining any protein at all are some of the problems often found down the pipeline. So we choose the most suitable strain and vector for this recombinant IFNB protein expression and adopt the most optimized expression condition and purification method. Finally, mild condition and subsequent cumbersome protein-refolding procedures ensure this IFNB protein is soluble.
IFNB (also known as IFN2) is a protein encoding gene that provides an instruction in making a protein named interferon type B (short name is IFN-beta). The protein encoded by this gene belongs to alpha/beta interferon family and has antiviral, antibacterial, and anticancer properties. IFNB is a key regulator in several pathways, such as cytokine-mediated signaling pathway and positive regulation of toll-like receptor 3 signaling pathway, and is involved in multiple biological processes, including adaptive immune response, defense response to virus and negative regulation of cytolysis, etc.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has antiviral activities.
基因功能參考文獻：
1. Fpv012 inhibits induction of IFNB. PMID: 23427153
2. RNA interference-mediated knockdown of ChMda5 showed that ChMda5 plays an important role in the IFN response of chicken cells to dsRNA PMID: 21444763
亞細胞定位：

Secreted.
蛋白家族：

Alpha/beta interferon family
數據庫鏈接：

KEGG: gga:554219

STRING: 9031.ENSGALP00000038687

UniGene: Gga.22865