Recombinant Bordetella pertussis Pertactin autotransporter (prn), partial

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中文名稱：

Recombinant Bordetella pertussis Pertactin autotransporter (prn), partial
品名簡稱：

Recombinant Bordetella pertussis Pertactin autotransporter protein, partial
貨號：

CSB-EP321224BUA2
說明書：

MSDS Datasheet
規格：

￥2328
圖片：
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

Greater than 95% as determined by SDS-PAGE.
生物活性：

Not Test
基因名：

prn
Uniprot No.：

P14283
別名：

P.93
種屬：

Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
蛋白長度：

Partial
來源：

E.coli
分子量：

17.6 kDa
表達區域：

41-142aa
氨基酸序列

IVKTGERQHGIHIQGSDPGGVRTASGTTIKVSGRQAQGILLENPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATLANVGDTWDDDGIALY
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

C-terminal 6xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

3-7 business days
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Agglutinogen that binds to eukaryotic cells; a process mediated by the R-G-D sequence. Pertactin may have a role in bacterial adhesion, and thus play a role in virulence. May contribute to the disease state of whooping cough.
基因功能參考文獻：
1. Prn-KO strains induced an increased production of pro-inflammatory cytokines by human and murine dendritic cell. PMID: 29559630
2. Multiple driving forces required for efficient secretion of autotransporter virulence proteins, such as pertactin. PMID: 25670852
3. Results indicate that the purified pertactin is a potential candidate as immunogen for preparation of diagnostic reagents and as a vaccine component. PMID: 20306653
亞細胞定位：

[Pertactin autotransporter]: Periplasm.; [Outer membrane protein P.69]: Secreted. Cell surface.; [Pertactin translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
數據庫鏈接：

KEGG: bpe:BP1054

STRING: 257313.BP1054