SAMM50 Recombinant Monoclonal Antibody
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中文名稱：SAMM50 Recombinant Monoclonal Antibody
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貨號：CSB-RA954130A0HU
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規(guī)格：￥1320
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圖片：
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Flow cytometric analysis of SAMM50 expression in HeLa cells using SAMM50 antibody. Green, isotype control; red, SAMM50. -
Immunocytochemical staining of HeLa cells with SAMM50 antibody. Nuclei were stained blue with DAPI; SAMM50 was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm. -
Western blotting analysis using SAMM50 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with SAMM50 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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其他：
產品詳情
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Uniprot No.：
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基因名：SAMM50
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別名：SAMM50 Sorting And Assembly Machinery Component; TRG-3; SAM50; YNL026W; CGI-51; OMP85; TOB55; Sorting And Assembly Machinery Component 50 Homolog; Transformation-Related Gene 3 Protein; Sorting And Assembly Machinery Component 50 Homolog (S. Cerevisiae); Sorting And Assembly Machinery 50kDa
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human SAMM50 protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：Rabbit IgG
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純化方式：Affinity-chromatography
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克隆號：15B8
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, FC, ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 FC 1:200-1:2000 ICC 1:100-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.
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基因功能參考文獻：
- The authors results demonstrate that SNP in the SAMM50 gene is significantly associated with the presence and severity of NAFLD in a Korean populations. PMID: 29271184
- Findings suggest a significant association between variants in COL13A1, ADIPOQ, SAMM50, and PNPLA3, and risk of NAFLD/elevated transaminase levels in Mexican adults with an admixed ancestry. PMID: 29307798
- SAMM50 affects the Drp1-dependent mitochondrial morphology. PMID: 27059175
- downregulation of SAM50 in BCR-ABL-expressing, but not normal CD34(+) human hematopoietic stem and progenitor cells (HSPCs) caused a significant decrease in growth, colony formation, and replating capacity. PMID: 26855047
- the integrity of MICOS and its efficient interaction with Sam50 are indispensable for cristae organization, which is relevant to mitochondrial function. PMID: 26530328
- Polymorphisms in the SAMM50 and PARVB genes in addition to those in the PNPLA3 gene were observed to be associated with the development and progression of NAFLD. PMID: 23535911
- The study describes a novel role of SAM50 in maintaining the mitochondrial shape and the morphology of cristae. PMID: 22252321
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亞細胞定位：Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm. Mitochondrion.
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蛋白家族：SAM50/omp85 family
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數據庫鏈接：
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