REEP2 Recombinant Monoclonal Antibody
產品詳情
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Uniprot No.：
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基因名：
REEP2
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別名：
REEP2; Receptor Accessory Protein 2; SGC32445; C5orf19; SPG72; Yip2d; Receptor Expression-Enhancing Protein 2; Chromosome 5 Open Reading Frame 19; SPG72A; SPG72B
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反應種屬：
Human, Rat
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免疫原：
Recombinant Human REEP2 protein
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免疫原種屬：
Homo sapiens (Human)
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標記方式：
Non-conjugated
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克隆類型：
Monoclonal
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抗體亞型：
Rabbit IgG
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純化方式：
Affinity-chromatography
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克隆號：
3G5
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濃度：
It differs from different batches. Please contact us to confirm it.
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保存緩沖液：
Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：
Liquid
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應用范圍：
ELISA, WB, FC
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推薦稀釋比：
| Application |
Recommended Dilution |
| WB |
1:1000-1:5000 |
| FC |
1:2000 |
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Protocols：
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儲存條件：
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能：
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors.
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基因功能參考文獻：
- Expression of the REEP1/REEP2 subfamily appears to be restricted to neuronal and neuronal-like exocytotic tissues, consistent with neuronally restricted symptoms of REEP1 genetic disorders. PMID: 24355597
- We have identified mutations in REEP2 in two families with relatively pure, early-onset hereditary spastic paraplegia, one with autosomal-dominant and the other with autosomal-recessive transmission. PMID: 24388663
- In mouse, Reep2 enhances sweet receptor function by a different mechanism than Reep1 uses to enhance olfactory receptor function. PMID: 20943918
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相關疾病：
Spastic paraplegia 72 (SPG72)
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亞細胞定位：
Membrane; Multi-pass membrane protein.
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蛋白家族：
DP1 family
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組織特異性：
Detected in brain, heart and skeletal muscle, and at low levels in placenta, kidney and pancreas. Expressed in circumvallate papillae.
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數據庫鏈接：
Most popular with customers
Flow cytometric analysis of REEP2 expression in HAP-1 cells using REEP2 antibody. Green, isotype control; red, REEP2.
Western blotting analysis using REEP2 antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with REEP2 antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
