RAB5C Recombinant Monoclonal Antibody
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中文名稱：RAB5C Recombinant Monoclonal Antibody
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貨號：CSB-RA903569A0HU
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規格：￥1320
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圖片：
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Flow cytometric analysis of RAB5C expression in HepG2 cells using RAB5C antibody. Green, isotype control; red, RAB5C. -
Immunocytochemical staining of HepG2 cells with RAB5C antibody. Nuclei were stained blue with DAPI; RAB5C was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm. -
Western blotting analysis using RAB5C antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with RAB5C antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：RAB5C; RAB5C, Member RAS Oncogene Family; RAB5CL; RABL; RAB5C, Member Of RAS Oncogene Family; Ras-Related Protein Rab-5C; L1880; RAB5L; RAB, Member Of RAS Oncogene Family-Like; EC 3.6.5.2
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反應種屬：Human, Mouse, Rat
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免疫原：Recombinant Human RAB5C protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：Rabbit IgG
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純化方式：Affinity-chromatography
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克隆號：12D6
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, FC, ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 FC 1:200-1:2000 ICC 1:100-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Protein transport. Probably involved in vesicular traffic.
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基因功能參考文獻：
- We identify RAB5C as a new candidate gene for type-2 diabetes risk with a functional role in endosomal type-2 diabetes module. Functional analysis shows that RAB5C is tyrosine phosphorylated. Data analysis reveals a tyrosine phosphorylation motif in the GTP binding site of RAB5C which may be targeted by insulin receptor. Insulin-dependent tyrosine phosphorylation of RAB5C is inhibited by overexpression of HACD3 (PTPLAD1). PMID: 30300385
- Enforced miR-509 expression in NALM6 cells reduced RAB5C mRNA and protein levels, and RAB5C was demonstrated to be a direct target of miR-509. PMID: 25368993
- PLP2 and RAB5C are binding partners of TPD52. PMID: 24604726
- Rab5C modulates Rac1-mediated cell motility. PMID: 24587345
- GTP-Rab5c also bound to AMAP1, and activation of Rab5c by EGFR signaling was necessary to promote the intracellular association of AMAP1 and PRKD2 PMID: 22734003
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亞細胞定位：Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome.
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蛋白家族：Small GTPase superfamily, Rab family
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數據庫鏈接：
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