ALPG Recombinant Monoclonal Antibody

說明書

中文名稱：

ALPG重組抗體
貨號：

CSB-RA001633MA1HU
規格：

￥1320
圖片：
The Binding Activity of Human ALPG with Anti-ALPG Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPG (CSB-MP001633HU) at 2 μg/mL can bind Anti-ALPG recombinant antibody , the EC₅₀ is 14.09-23.17 ng/mL.

The Binding Activity of Human ALPP with Anti-ALPP/ALPG Recombinant Antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPP (CSB-MP001632HU) at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody. The EC₅₀ is 4.478-5.236 ng/mL.
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品描述：

CSB-RA001633MA1HU是針對ALPG（堿性磷酸酶胎盤型）的重組單克隆抗體，靶向ALPG蛋白的特定表位。ALPG（亦稱PLAP）屬于堿性磷酸酶家族，主要參與磷酸酯代謝，并在胎盤組織及某些腫瘤細胞中特異性高表達，其表達水平與生殖細胞腫瘤、卵巢癌等疾病的生物學行為相關。本抗體采用重組蛋白免疫技術制備，經ELISA平臺嚴格驗證，展現出高特異性和靈敏性，可與天然及重組ALPG蛋白穩定結合，且不同批次間性能高度一致。其應用場景涵蓋體外檢測實驗，包括但不限于ELISA法檢測細胞裂解液或血清樣本中ALPG的定量分析，適用于生殖生物學、腫瘤標志物篩選及疾病機制研究等領域。該產品經過重組蛋白親和純化，確保低內毒素及交叉反應性，為科研人員提供穩定可靠的工具，滿足蛋白質功能研究、疾病模型構建及生物標志物開發等需求，所有數據均通過標準化的質控流程驗證。
Uniprot No.：

P10696
基因名：

ALPG
別名：

ALPG Recombinant Monoclonal Antibody
反應種屬：

Human
免疫原：

Recombinant Human ALPG protein
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Monoclonal
抗體亞型：

hIgG1
純化方式：

Affinity-chromatography
克隆號：

29A5
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Alkaline phosphatase that can hydrolyze various phosphate compounds.
基因功能參考文獻：
1. aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
2. These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
3. Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260
亞細胞定位：

Cell membrane; Lipid-anchor, GPI-anchor.
蛋白家族：

Alkaline phosphatase family
組織特異性：

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
數據庫鏈接：

HGNC: 441

OMIM: 171810

KEGG: hsa:251

STRING: 9606.ENSP00000295453

UniGene: Hs.333509

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