ACVR2A&ACVR2B Recombinant Monoclonal Antibody

說明書

中文名稱：

ACVR2A&ACVR2B Recombinant Monoclonal Antibody
貨號：

CSB-RA623829MA1HU
規格：

￥1320
圖片：
The Binding Activity of Human ACVR2A with Anti-ACVR2A&ACVR2B recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ACVR2A（CSB-MP001260HU1）at 2 μg/mL can bind Anti-ACVR2A&ACVR2B recombinant antibody . The EC₅₀ is 3.848-4.375 ng/mL.

The Binding Activity of Mouse ACVR2A with Anti-ACVR2A&ACVR2B recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse ACVR2A（CSB-MP001260MO1） at 2 μg/mL can bind Anti-ACVR2A&ACVR2B recombinant antibody. The EC₅₀ is 1.562-1.966 ng/mL.

The Binding Activity of Mouse Acvr2b with Anti-ACVR2A&ACVR2B recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Acvr2b（CSB-MP001261MO1） at 2 μg/mL can bind Anti-ACVR2A&ACVR2B recombinant antibody. The EC₅₀ is 3.560-4.235 ng/mL.

The Binding Activity of Human ACVR2B with Anti-ACVR2A&ACVR2B recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ACVR2B（CSB-MP623829HU） at 2 μg/mL can bind Anti-ACVR2A&ACVR2B recombinant antibody. The EC₅₀ is 2.983-3.438 ng/mL.

IHC image of CSB-RA623829MA1HU diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.

IHC image of CSB-RA623829MA1HU diluted at 1:200 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.

Immunofluorescence staining of SH-SY5Y cell with CSB-RA623829MA1HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L).

The purity of ACVR2A&ACVR2B was greater than 95% as determined by SEC-HPLC
其他：

產品詳情
產品評價

產品詳情

產品描述：

ACVR2B重組單克隆抗體（CUSABIO貨號：CSB-RA623829MA1HU）是針對激活素受體IIB型（ACVR2B）靶點開發的高特異性科研工具。ACVR2B作為TGF-β超家族的重要成員，通過介導激活素、肌抑素等配體信號傳導，在肌肉生長調控、代謝平衡及組織修復中發揮關鍵作用。本抗體經多種實驗平臺嚴格驗證，適用于ELISA、免疫組織化學（IHC）和免疫熒光（IF）檢測，其中IHC和IF實驗推薦使用1:50-1:200的稀釋范圍，可在多種樣本類型中實現清晰的靶標定位與信號特異性。實驗數據顯示，該抗體在石蠟包埋組織切片中能有效識別天然構象的ACVR2B蛋白，同時在細胞免疫熒光實驗中展現出優異的亞細胞定位能力，背景干擾低且批次穩定性優異。適用于研究肌肉發育相關機制、代謝性疾病模型、骨骼肌再生及纖維化病理過程等科研領域，為探究ACVR2B在細胞信號通路中的功能及其與相關疾病的關聯提供可靠檢測方案。
Uniprot No.：

P27037 Q13705
基因名：

ACVR2A&ACVR2B
別名：

Activin A receptor type IIA antibody; Activin receptor type 2A antibody; Activin receptor type IIA antibody; Activin receptor type-2A antibody; ACTR 2 antibody; ACTR IIA antibody; ACTR-IIA antibody; ACTR2 antibody; ACTRII antibody; ACTRIIA antibody; Acvr 2 antibody; Acvr 2A antibody; Acvr2 antibody; ACVR2A antibody; AVR2A_HUMAN antibody; OTTHUMP00000197918 antibody; Activin A receptor type IIB antibody; Activin receptor type 2B antibody; Activin receptor type IIB antibody; Activin receptor type-2B antibody; ActR IIB antibody; ACTR-IIB antibody; ActRIIB antibody; ACVR 2B antibody; ACVR2B antibody; AVR2B_HUMAN antibody; HTX4 antibody; MGC116908 antibody
反應種屬：

Human, Mouse
免疫原：

Recombinant Human ACVR2A&ACVR2B protein
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Monoclonal
抗體亞型：

hIgG1
純化方式：

Affinity-chromatography
克隆號：

7E5
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC, IF

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:5000-1:50000
IHC	1:50-1:200
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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