sulA Antibody, HRP conjugated

^{Rare Species}

說明書

產品詳情

產品名稱：

Rabbit anti-Escherichia coli sulA Polyclonal antibody
Uniprot No.：

P0AFZ5
基因名：

sulA
別名：

sulA antibody; sfiA antibody; b0958 antibody; JW0941 antibody; Cell division inhibitor SulA antibody
宿主：

Rabbit
反應種屬：

Escherichia coli
免疫原：

Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA)
免疫原種屬：

Escherichia coli
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU).
基因功能參考文獻：
1. In current work the recovery of division process of Escherichia coli cells after division arrest due to expression of SOS-response protein SulA was studied. Data indicate that cells are able to rapidly restore normal division; also nucleoid occlusion seems to be the main septum positioning mechanism during the process. PMID: 30188109
2. results indicate existence of a SulA-dependent pathway of high-pressure-induced cell filamentation and suggest involvement of the SOS response, and particularly of SulA, in high-pressure-mediated cell death in strains which are compromised in Lon function PMID: 15748989
3. Results found that the binding of SulA to FtsZ is necessary but not sufficient for inhibition of FtsZ polymerization. PMID: 18245292
蛋白家族：

SulA family
數據庫鏈接：

KEGG: ecj:JW0941

STRING: 316385.ECDH10B_1028

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