prfA Antibody

^{Rare Species}

說明書

產品詳情

Uniprot No.：

P22262
基因名：

prfA
別名：

Listeriolysin regulatory protein, prfA
反應種屬：

Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
免疫原：

Recombinant Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) Listeriolysin regulatory protein (1-237aa)
免疫原種屬：

Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Protein G
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors.
基因功能參考文獻：
1. Spontaneous loss of virulence in natural populations of Listeria monocytogenes due to mutations in hlyA and PrfA has been demonstrated. PMID: 28827366
2. PepP peptidase plays a role in posttranslational activation of the major virulence regulator, PrfA. PepP mediates recruitment of PrfA to the cytoplasmic membrane. PMID: 28396325
3. The truncated C-terminus of prfA considerably contributes to the strongly attenuated phenotype observed in vitro. PMID: 25813546
4. A novel bile exclusion locus bilE, coordinately regulated by sigmaB and PrfA, represents a new and important virulence factor in L. monocytogenes. PMID: 15686563
5. PrfA K220T amino acid substituted mutant gene in an EGDDeltaprfA strain did not restore the haemolytic and phosphatidylcholine phospholipase C activities, in contrast to the wild-type prfA gene. PMID: 17379709
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數據庫鏈接：

KEGG: lmo:lmo0200

STRING: 169963.lmo0200

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