lktA Antibody

Name: lktA Antibody
Brand: CUSABIO
SKU: CSB-PA314743EA01ESE

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文獻引用 (1) 說明書

產品詳情

產品描述：

CUSABIO produced the polyclonal antibody against lktA by immunizing rabbits with a synthetic peptide that corresponds to amino acids 715-953 of the recombinant Leukotoxin protein. The antiserum obtained from the rabbits was purified using protein G affinity chromatography, resulting in a purity level of 95% for the anti-lktA antibody.

This antibody is an unconjugated IgG that specifically reacts with Escherichia coli lktA. LktA is a virulence factor generated by the bacterium Mannheimia haemolytica, which targets and kills immune cells, particularly leukocytes, in the lungs of infected animals. The lktA polyclonal antibody developed by CUSABIO is suitable for detecting the lktA protein in ELISA.
產品名稱：

Rabbit anti-Mannheimia haemolytica lktA Polyclonal antibody
Uniprot No.：

P0C085
基因名：

lktA
別名：

lktA antibody; Leukotoxin antibody; Lkt antibody
宿主：

Rabbit
反應種屬：

Mannheimia haemolytica
免疫原：

Recombinant Mannheimia haemolytica Leukotoxin protein (715-953AA)
免疫原種屬：

Mannheimia haemolytica

標記方式：

Non-conjugated

本頁面中的產品，lktA Antibody (CSB-PA314743EA01ESE)，的標記方式是Non-conjugated。對于lktA Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA314743EB01ESE	lktA Antibody, HRP conjugated	ELISA
FITC	CSB-PA314743EC01ESE	lktA Antibody, FITC conjugated
Biotin	CSB-PA314743ED01ESE	lktA Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak hemolytic activity.
亞細胞定位：

Secreted. Host cell membrane; Multi-pass membrane protein.
蛋白家族：

RTX prokaryotic toxin (TC 1.C.11) family

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