cyp26b1 Antibody

^{Rare Species}

中文名稱：

cyp26b1兔多克隆抗體
貨號：

CSB-PA721935LA01DIL
規格：

￥440
圖片：
Western Blot
Positive WB detected in Recombinant protein
All lanes: cyp26b1 antibody at 4.4µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46 kDa
Observed band size: 51 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) cyp26b1 Polyclonal antibody
Uniprot No.：

Q6EIG3
基因名：

cyp26b1
別名：

cyp26b1Cytochrome P450 26B1 antibody; Cyp26B1 antibody; EC 1.14.13.- antibody; Retinoic acid-metabolizing cytochrome antibody
宿主：

Rabbit
反應種屬：

Zebrafish
免疫原：

Recombinant Zebrafish Cytochrome P450 26B1 protein (366-511AA)
免疫原種屬：

Danio rerio (Zebrafish) (Brachydanio rerio)

標記方式：

Non-conjugated

本頁面中的產品，cyp26b1 Antibody (CSB-PA721935LA01DIL)，的標記方式是Non-conjugated。對于cyp26b1 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA721935LB01DIL	cyp26b1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA721935LC01DIL	cyp26b1 Antibody, FITC conjugated
Biotin	CSB-PA721935LD01DIL	cyp26b1 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid (RA). Plays a role in skeletal development.
基因功能參考文獻：
1. we find that Cyp26 function is required in a short time window that overlaps the dynamic window of tenoblast condensation. However, cyp26b1 expression is largely restricted to regions between tenoblast condensations during this time PMID: 29227993
2. The data demonstrate that RA-induced osteoblast-preosteocyte transitioning has multiple effects on developing bone in Cyp26b1 mutants, ranging from gain to loss of bone, depending on the allelic strength, the developmental stage and the cellular context. PMID: 26903503
3. cyp26b1 is involved in limiting the activity of retinoic acid. Zygotic cyp26b1 was localized to presumptive rhombomere 3 and rhombomere 4 at early two-somite (2S) stage. Expression expands anteriorly to include rhombomere 2 at the 10S stage. PMID: 15661642
4. effects of the inhibitor rather than excess retinoic acid most closely phenocopied the jaw defects seen with the Cyp26B1 morpholino PMID: 17616924
5. Cyp26b1 is expressed within osteoblast cells, demonstrating that retinoic acid levels within these cells need to be tightly controlled PMID: 18927155
6. cyp26b1 mutants may serve as a model to study the etiology of human vertebral disorders such as Klippel-Feil anomaly PMID: 18927157
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亞細胞定位：

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
蛋白家族：

Cytochrome P450 family
數據庫鏈接：

KEGG: dre:324188

STRING: 7955.ENSDARP00000101543

UniGene: Dr.76359

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