ZRSR2 Antibody, FITC conjugated
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中文名稱：ZRSR2兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA618014LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) ZRSR2 Polyclonal antibody
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Uniprot No.：
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基因名：ZRSR2
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別名：CCCH type zinc finger antibody; CCCH type zinc finger; RNA binding motif and serine/arginine rich protein 2 antibody; MGC142014 antibody; MGC142040 antibody; Renal carcinoma antigen NY REN 20 antibody; Renal carcinoma antigen NY-REN-20 antibody; RNA-binding motif and serine/arginine rich protein 2 antibody; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2 antibody; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1 like 2 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1-like 2 antibody; U2AF1 RS2 antibody; U2AF1L2 antibody; U2AF1RS2 antibody; U2AF35-related protein antibody; U2AFM_HUMAN antibody; URP antibody; Zinc finger-; CCCH domain-; and RNA-binding motif-containing serine/arginine-rich protein 2 antibody; Zrsr2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 protein (191-372AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
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靶點(diǎn)詳情
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功能：Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.
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基因功能參考文獻(xiàn)：
- We conclude that the common clinical features of patients with an isolated mutation of ZRSR2 are a macrocytic anemia without leukopenia, thrombocytopenia or an increase in marrow blast percentage PMID: 28942350
- ZRSR2 has a role in RNA splicing; dysregulated splicing of U12-type introns is a characteristic feature of ZRSR2 mutations in myelodysplastic syndrome PMID: 25586593
- Data show that through recognition of a common splicing element, Urp facilitates distinct steps of U2- and U12-type intron splicing. PMID: 21041408
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亞細(xì)胞定位：Nucleus.
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組織特異性：Widely expressed.
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數(shù)據(jù)庫鏈接：
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