VPS25 Antibody

說明書

中文名稱：

VPS25兔多克隆抗體
貨號：

CSB-PA295359
規格：

￥1100
圖片：
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal liver tissue, Primary antibody: CSB-PA295359(VPS25 Antibody) at dilution 1/200 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
其他：

產品詳情

Uniprot No.：

Q9BRG1
基因名：

VPS25
別名：

Dermal papilla derived protein 9 antibody; Dermal papilla-derived protein 9 antibody; DERP9 antibody; EAP20 antibody; ELL associated protein of 20 kDa antibody; ELL-associated protein of 20 kDa antibody; ESCRT-II complex subunit VPS25 antibody; FAP20 antibody; HGNC:28122 antibody; hVps25 antibody; MGC10540 antibody; Vacuolar protein sorting 25 homolog (S. cerevisiae) antibody; Vacuolar protein sorting associated protein 25 antibody; Vacuolar protein-sorting-associated protein 25 antibody; VPS25 antibody; VPS25_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Full length fusion protein
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產品提供形式：

Liquid
應用范圍：

ELISA,WB

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
基因功能參考文獻：
1. mammalian ESCRTII is made up of hVps25p, hVps22p, and hVps36p and may be redundant, cargo-specific, or not required for protein sorting at the multivesicular body PMID: 16371348
亞細胞定位：

Cytoplasm. Endosome membrane. Nucleus, nucleoplasm. Note=Distributes diffusely throughout the cytoplasm and nucleoplasm, but exhibits a punctate distribution on coexpression with CHMP6.
蛋白家族：

VPS25 family
組織特異性：

Expressed at the mRNA level in kidney, liver, pancreas, and placenta. Lower levels of expression are found in heart, skeletal muscle, brain and lung.
數據庫鏈接：

HGNC: 28122

OMIM: 610907

KEGG: hsa:84313

STRING: 9606.ENSP00000253794

UniGene: Hs.500165

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