VKORC1L1 Antibody, HRP conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) VKORC1L1 Polyclonal antibody
Uniprot No.：

Q8N0U8
基因名：

VKORC1L1
別名：

VKORC1L1; Vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.
基因功能參考文獻：
1. This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. PMID: 29054760
2. a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration PMID: 24532791
3. VKORC1L1 is responsible for driving vitamin K-mediated intracellular antioxidation pathways critical to cell survival. PMID: 21367861
4. VKORC1L1 does not affect the variability of warfarin dose requirement in a Japanese patient population PMID: 17996924
亞細胞定位：

Endoplasmic reticulum membrane; Multi-pass membrane protein.
蛋白家族：

VKOR family
數據庫鏈接：

HGNC: 21492

OMIM: 608838

KEGG: hsa:154807

STRING: 9606.ENSP00000353998

UniGene: Hs.427232

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