USP45 Antibody

產(chǎn)品詳情

Uniprot No.：

Q70EL2
基因名：

USP45
別名：

USP45 antibody; Ubiquitin carboxyl-terminal hydrolase 45 antibody; EC 3.4.19.12 antibody; Deubiquitinating enzyme 45 antibody; Ubiquitin thioesterase 45 antibody; Ubiquitin-specific-processing protease 45 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the Internal region of Human USP45.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration.
基因功能參考文獻(xiàn)：
1. these results establish USP45 as a new regulator of XPF-ERCC1 crucial for efficient DNA repair PMID: 25538220
亞細(xì)胞定位：

Photoreceptor inner segment. Cytoplasm. Nucleus.
蛋白家族：

Peptidase C19 family
組織特異性：

Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 20080

KEGG: hsa:85015

STRING: 9606.ENSP00000333376

UniGene: Hs.143410

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