USP34 Antibody

說明書

產品詳情

Uniprot No.：

Q70CQ2
基因名：

USP34
別名：

Deubiquitinating enzyme 34 antibody; FLJ43910 antibody; KIAA0570 antibody; KIAA0729 antibody; MGC104459 antibody; Ubiquitin carboxyl terminal hydrolase 34 antibody; Ubiquitin carboxyl-terminal hydrolase 34 antibody; Ubiquitin specific processing protease 34 antibody; Ubiquitin specific protease 34 antibody; Ubiquitin thioesterase 34 antibody; Ubiquitin thiolesterase 34 antibody; Ubiquitin-specific-processing protease 34 antibody; UBP34_HUMAN antibody; USP 34 antibody; Usp34 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse
免疫原：

Human USP34
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
基因功能參考文獻：
1. the role of USP34 on epithelial-mesenchymal (EMT) induction and its effects on mammary epithelial stem cells, was investigated. PMID: 28499884
2. CONCLUSIONS: USP34 gene polymorphisms (rs17008097 and rs17008940) may not be associated with Polycystic ovary syndrome in the Han Chinese women. PMID: 25975428
蛋白家族：

Peptidase C19 family
組織特異性：

Expressed in brain at low level.
數據庫鏈接：

HGNC: 20066

OMIM: 615295

KEGG: hsa:9736

STRING: 9606.ENSP00000381577

UniGene: Hs.644708

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