ULK4 Antibody

說明書

中文名稱：

ULK4兔多克隆抗體
貨號：

CSB-PA853394ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA853394ESR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ULK4 Polyclonal antibody
Uniprot No.：

Q96C45
基因名：

ULK4
別名：

DKFZp 434E1822 antibody; DKFZp434E1822 antibody; FAM 7 C 1 antibody; FAM7C1 antibody; FLJ 20574 antibody; FLJ20574 antibody; REC 01035 antibody; REC01035 antibody; Serine/threonine-protein kinase ULK4 antibody; ULK 4 antibody; ULK4 antibody; ULK4_HUMAN antibody; Unc 51 like kinase 4 antibody; Unc 51 like kinase 4 (C. elegans) antibody; Unc-51-like kinase 4 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Serine/threonine-protein kinase ULK4 protein (1-290AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
基因功能參考文獻：
1. results indicate that genetic variations in LRP1 and ULK4 contribute to risk for presenting with an acute aortic dissection PMID: 27569546
2. Our findings indicate that ULK4 is a rare susceptibility gene for schizophrenia. PMID: 24284070
3. First identified as an ULK family kinase and predicted to be catalytically inactive. PMID: 12471243
4. Single-nucleotide polymorphism rs1052501 in ULK4 gene is associated with monoclonal gammopathy of undetermined significance and multiple myeloma PMID: 22945773
相關疾病：

Various anomalies in ULK4 gene have been reported for several cases of schizophrenia, schizophrenia plus bipolar disorder and autism. ULK4 gene has been proposed to be a rare susceptibility risk factor for a range of psychiatric diseases including schizophrenia.
蛋白家族：

Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
組織特異性：

Expressed in the brain, mainly in postmitotic neurons, including GABAergic neurons, but not in astrocytes (at protein level).
數據庫鏈接：

HGNC: 15784

OMIM: 617010

KEGG: hsa:54986

STRING: 9606.ENSP00000301831

UniGene: Hs.656192

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