UBTD1 Antibody

Name: UBTD1 Antibody
Brand: CUSABIO
SKU: CSB-PA884502LA01HU

說(shuō)明書(shū)

產(chǎn)品詳情

標(biāo)記方式：

Non-conjugated

本頁(yè)面中的產(chǎn)品，UBTD1 Antibody (CSB-PA884502LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于UBTD1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

標(biāo)記方式	貨號(hào)	產(chǎn)品名稱(chēng)	應(yīng)用
HRP	CSB-PA884502LB01HU	UBTD1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA884502LC01HU	UBTD1 Antibody, FITC conjugated
Biotin	CSB-PA884502LD01HU	UBTD1 Antibody, Biotin conjugated	ELISA

克隆類(lèi)型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. Is a TP53 downstream target gene that increases the stability of TP53 protein by promoting the ubiquitination and degradation of MDM2.
基因功能參考文獻(xiàn)：
1. Establish UBTD1 as a regulator of cellular senescence that mediates p53 function, and provide insights into the mechanism of Mdm2 inhibition that impacts p53 dynamics during cellular senescence and tumourigenesis. PMID: 25382750
2. Biochemical characterization of recombinant UBTD1 and UBE2D demonstrated that the two proteins form a stable, stoichiometric complex that can be purified to near homogeneity. PMID: 24211586
數(shù)據(jù)庫(kù)鏈接：

HGNC: 25683

OMIM: 616388

KEGG: hsa:80019

UniGene: Hs.500724

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