UBE2L6 Antibody, FITC conjugated
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中文名稱：UBE2L6兔多克隆抗體, FITC偶聯
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貨號：CSB-PA025466LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) UBE2L6 Polyclonal antibody
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Uniprot No.：
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基因名：
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別名：MGC40331 antibody; Retinoic acid induced gene B protein antibody; Retinoic acid-induced gene B protein antibody; RIG B antibody; RIG-B antibody; UB2L6_HUMAN antibody; UBCH 8 antibody; UbcH8 antibody; UBE2L6 antibody; Ubiquitin carrier protein antibody; Ubiquitin carrier protein L6 antibody; Ubiquitin conjugating enzyme E2L 6 antibody; Ubiquitin protein ligase antibody; Ubiquitin protein ligase L6 antibody; Ubiquitin-protein ligase L6 antibody; Ubiquitin/ISG15 conjugating enzyme E2 L6 antibody; Ubiquitin/ISG15-conjugating enzyme E2 L6 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Ubiquitin/ISG15-conjugating enzyme E2 L6 protein (13-153AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
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基因功能參考文獻：
- Depletion of either ISG15 or UBE2L6/UBCH8 resulted in enhanced endogenous autophagic flux. PMID: 28186990
- Data indicate that reduced expression of the ubiquitin-conjugating enzyme UbcH8 protein correlated with poor outcome in nasopharyngeal carcinoma (NPC) patients. PMID: 26506425
- gain and loss-of-function approaches show that UBCH8 and the ubiquitin-ligase SIAH1 physically interact with and target FLT3-ITD for proteasomal degradation PMID: 20508617
- Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 knockdown, respectively. PMID: 15670748
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蛋白家族：Ubiquitin-conjugating enzyme family
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組織特異性：Present in natural killer cells (at protein level).
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數據庫鏈接：
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