TTYH1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TTYH1 Polyclonal antibody
Uniprot No.：

Q9H313
基因名：

TTYH1
別名：

TTYH1; Protein tweety homolog 1; hTTY1
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Protein tweety homolog 1 protein (50-178AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Probable chloride channel. May be involved in cell adhesion.; Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
基因功能參考文獻：
1. In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells. PMID: 28607172
2. TTYH1 was not expressed in either the malignant or the control samples PMID: 25182704
3. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor. PMID: 24316981
4. Nedd4-2 differentially interacts with and regulates TTYH1-3 PMID: 18577513
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Tweety family
組織特異性：

Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung.
數據庫鏈接：

HGNC: 13476

OMIM: 605784

KEGG: hsa:57348

UniGene: Hs.268728

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