TSTA3 Antibody

說明書

產品詳情

Uniprot No.：

Q13630
基因名：

TSTA3
別名：

3 5 epimerase/4 reductase antibody; 5-epimerase-4-reductase antibody; anti TSTA3 antibody; EC 1.1.1.271 antibody; FCL_HUMAN antibody; FX antibody; GDP 4 keto 6 deoxy D mannose 3 5 epimerase 4 reductase antibody; GDP 4 keto 6 deoxy D mannose epimerase reductase antibody; GDP L fucose synthase antibody; GDP-4-keto-6-deoxy-D-mannose-3 antibody; GDP-L-fucose synthase antibody; P35B antibody; Protein FX antibody; Red cell NADP(H) binding protein antibody; Red cell NADP(H)-binding protein antibody; SDR4E1 antibody; Short chain dehydrogenase/reductase family 4E member 1 antibody; Short-chain dehydrogenase/reductase family 4E member 1 antibody; Tissue specific transplantation antigen 3 antibody; Tissue specific transplantation antigen P35B antibody; TSTA3 antibody; TSTA3 antibody antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the C-terminal region of Human FX.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
基因功能參考文獻：
1. tissue-specific transplantation antigen P35B may serve as a novel biomarker for prognosis of patients with esophageal squamous cell carcinoma. PMID: 29950151
2. The findings suggest that miR-125a-5p/miR-125b suppress the expression of TSTA3, which controls cell proliferation and invasion by regulating CXCR4 expression. In conclusion, a high expression of TSTA3 exerts a proto-oncogenic effect during carcinogenesis and serves as an independent molecular marker for breast cancerpatients. PMID: 26531722
3. Data indicate that the structure of GDP-l-fucose synthase (FX) reveals the key catalytic residues. PMID: 23774504
4. Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV PMID: 22528125
蛋白家族：

NAD(P)-dependent epimerase/dehydratase family, Fucose synthase subfamily
數據庫鏈接：

HGNC: 12390

OMIM: 137020

KEGG: hsa:7264

STRING: 9606.ENSP00000398803

UniGene: Hs.404119

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