TRIM10 Antibody

說明書

中文名稱：

TRIM10兔多克隆抗體
貨號：

CSB-PA871394ESR1HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA871394ESR1HU at dilution of 1:100
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) TRIM10 Polyclonal antibody
Uniprot No.：

Q9UDY6
基因名：

TRIM10
別名：

TRIM10 antibody; RFB30 antibody; RNF9 antibody; Tripartite motif-containing protein 10 antibody; B30-RING finger protein antibody; RING finger protein 9 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Tripartite motif-containing protein 10 protein (222-481AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

E3 ligase that plays an essential role in the differentiation and survival of terminal erythroid cells. May directly bind to PTEN and promote its ubiquitination, resulting in its proteasomal degradation and activation of hypertrophic signaling. In addition, plays a role in immune response regulation by repressing the phosphorylation of STAT1 and STAT2 in the interferon/JAK/STAT signaling pathway independent of its E3 ligase activity. Mechanistically, interacts with the intracellular domain of IFNAR1 and thereby inhibits the association between TYK2 and IFNAR1.
亞細胞定位：

Cytoplasm.
蛋白家族：

TRIM/RBCC family
數據庫鏈接：

HGNC: 10072

OMIM: 605701

KEGG: hsa:10107

STRING: 9606.ENSP00000397073

UniGene: Hs.709483

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